EWI2 prevents EGFR from clustering and endocytosis to reduce tumor cell movement and proliferation.

Fu, Chenying; Wang, Jie; Pallikkuth, Sandeep; Ding, Yingjun; Chen, Junxiong; Wren, Jonathan D; Yang, Yuchao; Wong, Kwong-Kwok; Kameyama, Hiroyasu; Jayaraman, Muralidharan; Munshi, Anupama; Tanaka, Takemi; Lidke, Keith A; Zhang, Xin A

Fu, Chenying; Wang, Jie; Pallikkuth, Sandeep; Ding, Yingjun; Chen, Junxiong; Wren, Jonathan D; Yang, Yuchao; Wong, Kwong-Kwok; Kameyama, Hiroyasu; Jayaraman, Muralidharan; Munshi, Anupama; Tanaka, Takemi; Lidke, Keith A; Zhang, Xin A.

Afiliação

Fu C; University of Oklahoma Health Sciences Center, Oklahoma City, USA.
Wang J; University of Oklahoma Health Sciences Center, Oklahoma City, USA.
Pallikkuth S; University of New Mexico, Albuquerque, USA.
Ding Y; University of Oklahoma Health Sciences Center, Oklahoma City, USA.
Chen J; University of Oklahoma Health Sciences Center, Oklahoma City, USA.
Wren JD; Oklahoma Medical Research Foundation, Oklahoma City, USA.
Yang Y; University of Oklahoma Health Sciences Center, Oklahoma City, USA.
Wong KK; University of Texas MD Anderson Cancer Center, Houston, USA.
Kameyama H; University of Oklahoma Health Sciences Center, Oklahoma City, USA.
Jayaraman M; University of Oklahoma Health Sciences Center, Oklahoma City, USA.
Munshi A; University of Oklahoma Health Sciences Center, Oklahoma City, USA.
Tanaka T; University of Oklahoma Health Sciences Center, Oklahoma City, USA.
Lidke KA; University of New Mexico, Albuquerque, USA.
Zhang XA; University of Oklahoma Health Sciences Center, Oklahoma City, USA. xin-zhang-1@ouhsc.edu.

Cell Mol Life Sci ; 79(7): 389, 2022 Jun 30.

Article em En | MEDLINE | ID: mdl-35773608

Assuntos

Antígenos CD; Endocitose; Receptores ErbB; Proteínas de Membrana; Neoplasias; Antígenos CD/metabolismo; Linhagem Celular Tumoral; Movimento Celular/fisiologia; Proliferação de Células/fisiologia; Transição Epitelial-Mesenquimal; Receptores ErbB/genética; Receptores ErbB/metabolismo; Humanos; Integrinas/metabolismo; Proteínas de Membrana/deficiência; Proteínas de Membrana/genética; Proteínas de Membrana/metabolismo; Neoplasias/genética; Neoplasias/metabolismo; Neoplasias/patologia

Palavras-chave

And integrin; Clathrin-mediated endocytosis; Epithelial-to-mesenchymal transition; MAPK signaling; Membrane spatial heterogeneity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antígenos CD / Endocitose / Receptores ErbB / Proteínas de Membrana / Neoplasias Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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