Ceramide de novo synthesis in non-alcoholic fatty liver disease: Pathogenic mechanisms and therapeutic perspectives.

Yu, Xiao-Dong; Wang, Jiong-Wei

Yu, Xiao-Dong; Wang, Jiong-Wei.

Afiliação

Yu XD; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Nanomedicine Translational Research Programme, Centre for NanoMedicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Wang JW; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Nanomedicine Translational Research Programme, Centre for NanoMedicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Cardiovascular Research Institute (CVRI), National University Heart Centre Singapore (NUHCS), Singapore, Singapore; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapo

Biochem Pharmacol ; 202: 115157, 2022 08.

Article em En | MEDLINE | ID: mdl-35777449

Assuntos

Resistência à Insulina; Neoplasias Hepáticas; Hepatopatia Gordurosa não Alcoólica; Ceramidas/metabolismo; Hepatócitos/metabolismo; Humanos; Fígado/metabolismo; Neoplasias Hepáticas/metabolismo; Hepatopatia Gordurosa não Alcoólica/metabolismo

Palavras-chave

Ceramide; Ceramide de novo synthesis; Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Sphingolipids; Therapeutic target

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Hepatopatia Gordurosa não Alcoólica / Neoplasias Hepáticas Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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