Mid-short-term risk factors for chronic renal failure in children with posterior urethral valve.
Pediatr Surg Int
; 38(9): 1321-1326, 2022 Sep.
Article
em En
| MEDLINE
| ID: mdl-35779105
ABSTRACT
OBJECTIVES:
To analyze the mid-short-term risk factors for chronic renal failure (CRF) in children with posterior urethral valve (PUV) after valve ablation. MATERIALS ANDMETHODS:
A retrospective study of 143 patients with PUV who underwent operation was performed. Patients were divided into CRF group (n = 39) and non-CRF group (n = 104). Clinical data of both groups such as the first resection age, last resection age, number of operations, the maximal detrusor pressure (Pdetmax), and vesicoureteral reflux (VUR) were collected and analyzed.RESULTS:
The first resection age, last resection age, and the Pdetmax of patients in the CRF group were higher than those of patients in the non-CRF group (P < 0.05). Multiple regression analysis showed that the indicators related to chronic renal failure were last resection age (ß = 1.034, P < 0.05) and Pdetmax (ß = 1.068, P < 0.05). The cut-off value of last resection age was 35.5 months, Pdetmax was 41.65 cmH2O. There was positive correlation of final blood creatinine with last resection age and Pdetmax.CONCLUSION:
The last resection age and Pdetmax are the risk factors of chronic renal failure in children with PUV. A Pdetmax of lower than 41.65 cmH2O indicates a good prognosis of renal function in patients with PUV.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Uretra
/
Falência Renal Crônica
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article