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Design and Measurement of Drug Tissue Concentration Asymmetry and Tissue Exposure-Effect (Tissue PK-PD) Evaluation.
Zang, Richard; Barth, Aline; Wong, Harvey; Marik, Jan; Shen, Jie; Lade, Julie; Grove, Kerri; Durk, Matthew R; Parrott, Neil; Rudewicz, Patrick J; Zhao, Sylvia; Wang, Tao; Yan, Zhengyin; Zhang, Donglu.
Afiliação
  • Zang R; IDEAYA Biosciences, South San Francisco, California 94080, United States.
  • Barth A; Global Blood Therapeutics, South San Francisco, California 94080, United States.
  • Wong H; The University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
  • Marik J; Genentech, South San Francisco, California 98080, United States.
  • Shen J; AbbVie, Irvine, California 92612, United States.
  • Lade J; Amgen Inc., South San Francisco, California 94080, United States.
  • Grove K; Novartis, Emeryville, California 94608, United States.
  • Durk MR; Genentech, South San Francisco, California 98080, United States.
  • Parrott N; Roche Innovation Centre, Basel CH-4070, Switzerland.
  • Rudewicz PJ; Novartis, Emeryville, California 94608, United States.
  • Zhao S; Novartis, Shanghai 201203, China.
  • Wang T; Coherus BioSciences, Redwood City, California 94605, United States.
  • Yan Z; Genentech, South San Francisco, California 98080, United States.
  • Zhang D; Genentech, South San Francisco, California 98080, United States.
J Med Chem ; 65(13): 8713-8734, 2022 07 14.
Article em En | MEDLINE | ID: mdl-35790118
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasma / Descoberta de Drogas Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasma / Descoberta de Drogas Idioma: En Ano de publicação: 2022 Tipo de documento: Article