Study of the relationship between FT3, FT4, and TSH with bone resorption indices in men with hypothyroidism.
J Popul Ther Clin Pharmacol
; 29(2): e33-e39, 2022.
Article
em En
| MEDLINE
| ID: mdl-35848195
ABSTRACT
AIM:
This study aimed to find the effect of hypothyroidism in men on metabolism and bone mineral density.METHOD:
The study included a patients group of 90 men suffering from hypothyroidism and 120 healthy subjects as a control group. The study comprised the estimation of the concentration of Blood free triiodothyronine (FT3), free thyroid hormone (FT4), thyroid stimulating hormone (TSH), bone resorption index type I collagen C-terminal peptide (CTX-1), the serum calcium (Ca2+), serum phosphorus (Pi3+), the bone mineral density of the lumbar spine and femoral neck.RESULTS:
In the hypothyroidism men group (1) the bone mass was lower than the control group with significant differences, (2) the bone resorption index CTX-1 was significantly higher than that in the control group and calcium and phosphorus were not different from those in healthy control subjects, and (3) TSH was positively correlated with CTX-1. Male TSH and CTX-1 levels were positively correlated.CONCLUSIONS:
There is bone loss in men with hypothyroidism, which may be related to increased bone resorption.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Reabsorção Óssea
/
Hipotireoidismo
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article