Combining TMZ and SB225002 induces changes of CXCR2 and VEGFR signalling in primary human endothelial cells <i>in vitro</i>.

Urbantat, Ruth M; Jelgersma, Claudius; Vajkoczy, Peter; Brandenburg, Susan; Acker, Gueliz

Combining TMZ and SB225002 induces changes of CXCR2 and VEGFR signalling in primary human endothelial cells in vitro.

Urbantat, Ruth M; Jelgersma, Claudius; Vajkoczy, Peter; Brandenburg, Susan; Acker, Gueliz.

Afiliação

Urbantat RM; Department of Neurosurgery, CharitéUniversitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, HumboldtUniversität zu Berlin, D10117 Berlin, Germany.
Jelgersma C; Department of Neurosurgery, CharitéUniversitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, HumboldtUniversität zu Berlin, D10117 Berlin, Germany.
Vajkoczy P; Department of Neurosurgery, CharitéUniversitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, HumboldtUniversität zu Berlin, D10117 Berlin, Germany.
Brandenburg S; Department of Neurosurgery, CharitéUniversitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, HumboldtUniversität zu Berlin, D10117 Berlin, Germany.
Acker G; Department of Neurosurgery, CharitéUniversitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, HumboldtUniversität zu Berlin, D10117 Berlin, Germany.

Oncol Rep ; 48(3)2022 09.

Article em En | MEDLINE | ID: mdl-35856448

Assuntos

Células Endoteliais; Glioblastoma; Células Endoteliais/metabolismo; Glioblastoma/tratamento farmacológico; Glioblastoma/genética; Glioblastoma/metabolismo; Humanos; Interleucina-8/genética; Interleucina-8/metabolismo; Compostos de Fenilureia; Proteínas Proto-Oncogênicas c-bcl-2/metabolismo; Receptores de Interleucina-8B/metabolismo; Temozolomida/farmacologia; Temozolomida/uso terapêutico; Fator A de Crescimento do Endotélio Vascular/metabolismo

Palavras-chave

CXC motif chemokine ligand 2; SB225002; human umbilical vein endothelial cells; interleukin8; temozolomide; vascular endothelial growth factor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glioblastoma / Células Endoteliais Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glioblastoma / Células Endoteliais Idioma: En Ano de publicação: 2022 Tipo de documento: Article