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Lighting the way to host-directed immunotherapeutics.
van Tol, Sarah; Hage, Adam; Rajsbaum, Ricardo.
Afiliação
  • van Tol S; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA. Electronic address: savantol@utmb.edu.
  • Hage A; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA. Electronic address: arhage@utmb.edu.
  • Rajsbaum R; Center for Virus-Host-Innate-Immunity, RBHS Institute for Infectious and Inflammatory Diseases, and Department of Medicine, New Jersey Medical School, Rutgers-The State University of New Jersey, Newark, NJ, USA. Electronic address: ricardo.rajsbaum@rutgers.edu.
Cell Chem Biol ; 29(7): 1067-1070, 2022 07 21.
Article em En | MEDLINE | ID: mdl-35868235
ABSTRACT
Developing broad-spectrum, host-directed antiviral therapeutics can be adapted to combat emerging viruses. In this issue of Cell Chemical Biology, Maarifi and colleagues implement a Nano luciferase reporter-based protein complementation assay to screen for small molecules and identify Gilteritinib, which enhances interferon induction and antagonizes virus replication.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Replicação Viral Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Replicação Viral Idioma: En Ano de publicação: 2022 Tipo de documento: Article