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Pharmacokinetics and metabolism in mouse retina of bis-allylic deuterated docosahexaenoic acid (D-DHA), a new dry AMD drug candidate.
James, Genevieve; Bohannan, Whitney; Adewunmi, Eniola; Schmidt, Karsten; Park, Hui Gyu; Shchepinov, Mikhail S; Agbaga, Martin-Paul; Brenna, J Thomas.
Afiliação
  • James G; Dell Pediatric Research Institute, University of Texas at Austin, Austin, TX, USA. Electronic address: gejames@utexas.edu.
  • Bohannan W; Departments of Cell Biology, 608 Stanton L, Young Blvd, Oklahoma City, OK, 73104, USA; Departments of Ophthalmology and Dean McGee Eye Institute, 608 Stanton L, Young Blvd, Oklahoma City, OK, 73104, USA; University of Oklahoma Health Sciences Center, 608 Stanton L, Young Blvd, Oklahoma City, OK, 731
  • Adewunmi E; Departments of Cell Biology, 608 Stanton L, Young Blvd, Oklahoma City, OK, 73104, USA; Departments of Ophthalmology and Dean McGee Eye Institute, 608 Stanton L, Young Blvd, Oklahoma City, OK, 73104, USA; University of Oklahoma Health Sciences Center, 608 Stanton L, Young Blvd, Oklahoma City, OK, 731
  • Schmidt K; Retrotope, Inc., 4300 El Camino Real, Suite 201, Los Altos, CA, 94022, USA. Electronic address: karsten.schmidt@retrotope.com.
  • Park HG; Dell Pediatric Research Institute, University of Texas at Austin, Austin, TX, USA. Electronic address: hi.park@austin.utexas.edu.
  • Shchepinov MS; Retrotope, Inc., 4300 El Camino Real, Suite 201, Los Altos, CA, 94022, USA. Electronic address: misha@retrotope.com.
  • Agbaga MP; Departments of Cell Biology, 608 Stanton L, Young Blvd, Oklahoma City, OK, 73104, USA; Departments of Ophthalmology and Dean McGee Eye Institute, 608 Stanton L, Young Blvd, Oklahoma City, OK, 73104, USA; University of Oklahoma Health Sciences Center, 608 Stanton L, Young Blvd, Oklahoma City, OK, 731
  • Brenna JT; Dell Pediatric Research Institute, University of Texas at Austin, Austin, TX, USA. Electronic address: tbrenna@austin.utexas.edu.
Exp Eye Res ; 222: 109193, 2022 09.
Article em En | MEDLINE | ID: mdl-35870486
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácidos Docosa-Hexaenoicos / Atrofia Geográfica Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácidos Docosa-Hexaenoicos / Atrofia Geográfica Idioma: En Ano de publicação: 2022 Tipo de documento: Article