Discovery of Novel Dual Adenosine A2A and A1 Receptor Antagonists with 1H-Pyrazolo[3,4-d]pyrimidin-6-amine Core Scaffold as Anti-Parkinson's Disease Agents.

Jung, Juyoung; Lee, Yoonsuk; Moon, An-Na; Ann, Jihyae; Jeong, Jin Ju; Do, Nayeon; Lee, Jeewoo

Discovery of Novel Dual Adenosine A_2A and A₁ Receptor Antagonists with 1H-Pyrazolo[3,4-d]pyrimidin-6-amine Core Scaffold as Anti-Parkinson's Disease Agents.

Jung, Juyoung; Lee, Yoonsuk; Moon, An-Na; Ann, Jihyae; Jeong, Jin Ju; Do, Nayeon; Lee, Jeewoo.

Afiliação

Jung J; iLeadBMS Co., Ltd., Hwaseong-si 18469, Korea.
Lee Y; iLeadBMS Co., Ltd., Hwaseong-si 18469, Korea.
Moon AN; iLeadBMS Co., Ltd., Hwaseong-si 18469, Korea.
Ann J; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, Korea.
Jeong JJ; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, Korea.
Do N; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, Korea.
Lee J; Laboratory of Medicinal Chemistry, College of Pharmacy, Seoul National University, Seoul 08826, Korea.

Pharmaceuticals (Basel) ; 15(8)2022 Jul 25.

Article em En | MEDLINE | ID: mdl-35893746