Polarization disorder of decidual NK cells in unexplained recurrent spontaneous abortion revealed by single-cell transcriptome analysis.

Pan, Dingchen; Liu, Qian; Du, Le; Yang, Yang; Jiang, Guojing

Pan, Dingchen; Liu, Qian; Du, Le; Yang, Yang; Jiang, Guojing.

Afiliação

Pan D; Obstetrics and Gynaecology Department, Shuguang Hospital of Shanghai University of Traditional Chinese Medicine, 528 Zhangheng Road, Shanghai, 201203, China.
Liu Q; Shuguang Clinical College, Shanghai University of Traditional Chinese Medicine, 528 Zhangheng Road, Shanghai, 201203, China.
Du L; Shuguang Clinical College, Shanghai University of Traditional Chinese Medicine, 528 Zhangheng Road, Shanghai, 201203, China.
Yang Y; Experiment Centre for Science and Technology, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai, 201203, China. yyang_shutcm@126.com.
Jiang G; Obstetrics and Gynaecology Department, Shuguang Hospital of Shanghai University of Traditional Chinese Medicine, 528 Zhangheng Road, Shanghai, 201203, China. myjoice2021@163.com.

Reprod Biol Endocrinol ; 20(1): 108, 2022 Jul 27.

Article em En | MEDLINE | ID: mdl-35897028

Assuntos

Aborto Habitual; Decídua; Aborto Habitual/metabolismo; Decídua/metabolismo; Feminino; Perfilação da Expressão Gênica; Humanos; Células Matadoras Naturais; Gravidez; Análise de Célula Única; Transcriptoma; Trofoblastos/metabolismo

Palavras-chave

Decidual nature killer cell; Extracellular matrix; Immune tolerance; Maternalfetal interface; Single-cell RNA-seq; Unexplained recurrent spontaneous abortion

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aborto Habitual / Decídua Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

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XML

PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aborto Habitual / Decídua Idioma: En Ano de publicação: 2022 Tipo de documento: Article