Increased Expression and Amplification of <i>bla</i><sub>KPC-2</sub> Contributes to Resistance to Ceftazidime/Avibactam in a Sequence Type 11 Carbapenem-Resistant Klebsiella pneumoniae Strain.

Li, Xinhui; Zhang, Jisheng; Yang, Chengru; Li, Jie; Wang, Jianmin; Huang, Wan; Zeng, Lingyi; Liang, Xushan; Long, Wenzhang; Zhang, Xiaoli

Increased Expression and Amplification of bla_KPC-2 Contributes to Resistance to Ceftazidime/Avibactam in a Sequence Type 11 Carbapenem-Resistant Klebsiella pneumoniae Strain.

Li, Xinhui; Zhang, Jisheng; Yang, Chengru; Li, Jie; Wang, Jianmin; Huang, Wan; Zeng, Lingyi; Liang, Xushan; Long, Wenzhang; Zhang, Xiaoli.

Afiliação

Li X; Department of Microbiology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Zhang J; Department of Microbiology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Yang C; Department of Microbiology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Li J; Department of Microbiology, The First Affiliated Hospital of Jiamusi University, Jiamusi, China.
Wang J; Department of Microbiology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Huang W; Department of Microbiology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Zeng L; Department of Microbiology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Liang X; Department of Microbiology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Long W; Department of Microbiology, Jiaxing Maternity and Child Health Care Hospital, Jiaxing, China.
Zhang X; Department of Microbiology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.

Microbiol Spectr ; 10(4): e0095522, 2022 08 31.

Article em En | MEDLINE | ID: mdl-35900090

Assuntos

Ceftazidima; Infecções por Klebsiella; Antibacterianos/farmacologia; Antibacterianos/uso terapêutico; Compostos Azabicíclicos; Proteínas de Bactérias/genética; Proteínas de Bactérias/metabolismo; Carbapenêmicos/farmacologia; Carbapenêmicos/uso terapêutico; Ceftazidima/farmacologia; Ceftazidima/uso terapêutico; Humanos; Infecções por Klebsiella/tratamento farmacológico; Klebsiella pneumoniae/genética; Testes de Sensibilidade Microbiana; beta-Lactamases/genética

Palavras-chave

IS26; blaKPC-2; carbapenem-resistant Klebsiella pneumoniae; ceftazidime-avibactam resistance

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por Klebsiella / Ceftazidima Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por Klebsiella / Ceftazidima Idioma: En Ano de publicação: 2022 Tipo de documento: Article