Case Report: Papillary Lesions at the Mouth Floor May Mimic Sialadenoma Papilliferum.
Pathol Oncol Res
; 28: 1610352, 2022.
Article
em En
| MEDLINE
| ID: mdl-35911440
ABSTRACT
Salivary gland tumor Sialadenoma papilliferum (SialP) clinically resembles papillary epithelial lesions, such as squamous papilloma (SqP) or verrucous leukoplakia. Pathological sampling including an adequate depth of both the mucosa and submucosa layer is required for discrimination between the diseases. Though ductal proliferation in the submucosa is characteristic in SialP, papillary lesions arising at the mouth floor, specifically near the ductal orifice, are more problematic. Salivary gland ductal ectasia, along with the overlying papillary hyperplasia, may mimic the biphasic tumorous growth pattern of SialP, making discrimination extremely difficult. Further cellular dysplasia in the papillary mucosal lesion raises the possibility of malignant transformation in a known benign lesion, SialP. Herein, we present a case of SqP at the mouth floor which mimicked both clinical and pathological features of SialP and compared it with a definite case of SialP. Moreover, we discuss major differential points that clinicians and pathologists should consider during diagnosis of oral papillary lesions arising near the salivary glands.
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Base de dados:
MEDLINE
Assunto principal:
Papiloma
/
Neoplasias das Glândulas Salivares
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article