<i>XDH</i> genotypes through gene-gene interactions with <i>NUDT15</i> affect azathioprine-induced leukopenia in Chinese patients.

Liu, Jiquan; Wen, Zhiyong; Huang, Sichao; Zhang, Xiaomin; Ai, Xinbo; Qian, Jiajian

XDH genotypes through gene-gene interactions with NUDT15 affect azathioprine-induced leukopenia in Chinese patients.

Liu, Jiquan; Wen, Zhiyong; Huang, Sichao; Zhang, Xiaomin; Ai, Xinbo; Qian, Jiajian.

Afiliação

Liu J; Department of Gastroenterology, Zhuhai People's Hospital (Zhuhai hospital affiliated with Jinan University), Zhuhai, 519000, PR China.
Wen Z; Department of Pharmacy, Zhuhai People's Hospital (Zhuhai hospital affiliated with Jinan University), Zhuhai, 519000, PR China.
Huang S; Department of Pharmacy, Zhuhai People's Hospital (Zhuhai hospital affiliated with Jinan University), Zhuhai, 519000, PR China.
Zhang X; Department of Pharmacy, The Fifth Affiliated Hospital of Zunyi Medical University, Zhuhai (Zhuhai Sixth People's Hospital), Zhuhai, 519000, PR China.
Ai X; Department of Gastroenterology, Zhuhai People's Hospital (Zhuhai hospital affiliated with Jinan University), Zhuhai, 519000, PR China.
Qian J; Department of Pharmacy, Zhuhai People's Hospital (Zhuhai hospital affiliated with Jinan University), Zhuhai, 519000, PR China.

Pharmacogenomics ; 23(12): 671-682, 2022 08.

Article em En | MEDLINE | ID: mdl-35916133

Assuntos

Azatioprina; Leucopenia; Pirofosfatases; Xantina Desidrogenase; Azatioprina/efeitos adversos; China; Genótipo; Humanos; Leucopenia/induzido quimicamente; Leucopenia/genética; Pirofosfatases/genética; Sulfurtransferases/genética; Xantina Desidrogenase/genética

Palavras-chave

GMPS; MOCOS; NUDT15; XDH; adverse reactions; azathioprine

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirofosfatases / Azatioprina / Xantina Desidrogenase / Leucopenia Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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