Testing the link between isoaspartate and Alzheimer's disease etiology.

Wang, Jijing; Guo, Cong; Meng, Zhaowei; Zwan, Marissa D; Chen, Xin; Seelow, Sven; Lundström, Susanna L; Rodin, Sergey; Teunissen, Charlotte E; Zubarev, Roman A

Wang, Jijing; Guo, Cong; Meng, Zhaowei; Zwan, Marissa D; Chen, Xin; Seelow, Sven; Lundström, Susanna L; Rodin, Sergey; Teunissen, Charlotte E; Zubarev, Roman A.

Afiliação

Wang J; Department of Medical Biophysics and Biochemistry, Karolinska Institutet, Stockholm, Sweden.
Guo C; Department of Physics and International Centre for Quantum and Molecular Structures, College of Sciences, Shanghai University, Shanghai, China.
Meng Z; Department of Medical Biophysics and Biochemistry, Karolinska Institutet, Stockholm, Sweden.
Zwan MD; Neurochemistry Laboratory, Department of Clinical Chemistry, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.
Chen X; Department of Physics and International Centre for Quantum and Molecular Structures, College of Sciences, Shanghai University, Shanghai, China.
Seelow S; Department of Medical Biophysics and Biochemistry, Karolinska Institutet, Stockholm, Sweden.
Lundström SL; Department of Medical Biophysics and Biochemistry, Karolinska Institutet, Stockholm, Sweden.
Rodin S; Department of Medical Biophysics and Biochemistry, Karolinska Institutet, Stockholm, Sweden.
Teunissen CE; Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Zubarev RA; Neurochemistry Laboratory, Department of Clinical Chemistry, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

Alzheimers Dement ; 19(4): 1491-1502, 2023 04.

Article em En | MEDLINE | ID: mdl-35924765

Assuntos

Doença de Alzheimer; Humanos; Doença de Alzheimer/metabolismo; Ácido Isoaspártico/química; Ácido Isoaspártico/metabolismo; Peptídeos beta-Amiloides/metabolismo; Proteínas tau/metabolismo; Proteínas Sanguíneas/metabolismo; Encéfalo/metabolismo

Palavras-chave

Alzheimer's disease (AD); aging; blood analysis; deamidation; enzyme-linked immunosorbent assay (ELISA); human serum albumin (HSA); in vitro diagnostics; mass spectrometry; protein aggregation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Idioma: En Ano de publicação: 2023 Tipo de documento: Article