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Rotational constriction of curcuminoids impacts 5-lipoxygenase and mPGES-1 inhibition and evokes a lipid mediator class switch in macrophages.
Rao, Zhigang; Caprioglio, Diego; Gollowitzer, André; Kretzer, Christian; Imperio, Daniela; Collado, Juan A; Waltl, Lorenz; Lackner, Sandra; Appendino, Giovanni; Muñoz, Eduardo; Temml, Veronika; Werz, Oliver; Minassi, Alberto; Koeberle, Andreas.
Afiliação
  • Rao Z; Michael Popp Institute and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck 6020, Austria.
  • Caprioglio D; Department of Drug Science, University of Piemonte Orientale, 28100 Novara, Italy.
  • Gollowitzer A; Michael Popp Institute and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck 6020, Austria.
  • Kretzer C; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, Jena 07743, Germany.
  • Imperio D; Department of Drug Science, University of Piemonte Orientale, 28100 Novara, Italy.
  • Collado JA; Department of Cellular Biology, Physiology and Immunology, University of Cordoba, 14071, Cordoba, Spain; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), 14004, Cordoba, Spain; Hospital Universitario Reina Sofia, 14004, Cordoba, Spain.
  • Waltl L; Michael Popp Institute and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck 6020, Austria.
  • Lackner S; Michael Popp Institute and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck 6020, Austria.
  • Appendino G; Department of Drug Science, University of Piemonte Orientale, 28100 Novara, Italy.
  • Muñoz E; Department of Cellular Biology, Physiology and Immunology, University of Cordoba, 14071, Cordoba, Spain; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), 14004, Cordoba, Spain; Hospital Universitario Reina Sofia, 14004, Cordoba, Spain.
  • Temml V; Institute of Pharmacy, Department of Pharmaceutical and Medicinal Chemistry, Paracelsus Medical University Salzburg, Salzburg 5020, Austria.
  • Werz O; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, Jena 07743, Germany.
  • Minassi A; Department of Drug Science, University of Piemonte Orientale, 28100 Novara, Italy. Electronic address: alberto.minassi@uniupo.it.
  • Koeberle A; Michael Popp Institute and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck 6020, Austria. Electronic address: andreas.koeberle@uibk.ac.at.
Biochem Pharmacol ; 203: 115202, 2022 09.
Article em En | MEDLINE | ID: mdl-35932797
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Araquidonato 5-Lipoxigenase / Curcumina / Prostaglandina-E Sintases Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Araquidonato 5-Lipoxigenase / Curcumina / Prostaglandina-E Sintases Idioma: En Ano de publicação: 2022 Tipo de documento: Article