Discovery of novel natural products as dual MNK/PIM inhibitors for acute myeloid leukemia treatment: Pharmacophore modeling, molecular docking, and molecular dynamics studies.

Mohamed, Linda M; Eltigani, Maha M; Abdallah, Marwa H; Ghaboosh, Hiba; Bin Jardan, Yousef A; Yusuf, Osman; Elsaman, Tilal; Mohamed, Magdi A; Alzain, Abdulrahim A

Mohamed, Linda M; Eltigani, Maha M; Abdallah, Marwa H; Ghaboosh, Hiba; Bin Jardan, Yousef A; Yusuf, Osman; Elsaman, Tilal; Mohamed, Magdi A; Alzain, Abdulrahim A.

Afiliação

Mohamed LM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Gezira, Gezira, Sudan.
Eltigani MM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Gezira, Gezira, Sudan.
Abdallah MH; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Gezira, Gezira, Sudan.
Ghaboosh H; Department of Pharmaceutics, Faculty of Pharmacy, University of Gezira, Gezira, Sudan.
Bin Jardan YA; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Yusuf O; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Elsaman T; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
Mohamed MA; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
Alzain AA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Gezira, Gezira, Sudan.