Impact of Seasonal Coronavirus Antibodies on Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine Responses in Solid Organ Transplant Recipients.
Clin Infect Dis
; 76(3): e495-e498, 2023 02 08.
Article
em En
| MEDLINE
| ID: mdl-35959783
ABSTRACT
Antibody responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination are reduced in solid organ transplant recipients (SOTRs). We report that increased levels of preexisting antibodies to seasonal coronaviruses are associated with decreased antibody response to SARS-CoV-2 vaccination in SOTRs, supporting that antigenic imprinting modulates vaccine responses in SOTRs.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Vacinas
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Transplante de Órgãos
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Vacinas contra COVID-19
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COVID-19
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article