MALT1 regulates Th2 and Th17 differentiation <i>via</i> NF-&#954;B and JNK pathways, as well as correlates with disease activity and treatment outcome in rheumatoid arthritis.

Wang, Qiubo; Wang, Yapeng; Liu, Qingyang; Chu, Ying; Mi, Rui; Jiang, Fengying; Zhao, Jingjing; Hu, Kelong; Luo, Ran; Feng, Yufeng; Lee, Harrison; Zhou, Dong; Mi, Jingyi; Deng, Ruoyu

MALT1 regulates Th2 and Th17 differentiation via NF-κB and JNK pathways, as well as correlates with disease activity and treatment outcome in rheumatoid arthritis.

Wang, Qiubo; Wang, Yapeng; Liu, Qingyang; Chu, Ying; Mi, Rui; Jiang, Fengying; Zhao, Jingjing; Hu, Kelong; Luo, Ran; Feng, Yufeng; Lee, Harrison; Zhou, Dong; Mi, Jingyi; Deng, Ruoyu.

Afiliação

Wang Q; Department of Clinical Laboratory, Wuxi 9th People's Hospital Affiliated to Soochow University, Wuxi, China.
Wang Y; Department of Orthopedics, Wuxi 9th People's Hospital Affiliated to Soochow University, Wuxi, China.
Liu Q; Department of Clinical Laboratory, Wuxi 9th People's Hospital Affiliated to Soochow University, Wuxi, China.
Chu Y; Department of Clinical Laboratory, Wuxi 9th People's Hospital Affiliated to Soochow University, Wuxi, China.
Mi R; Department of Clinical Laboratory, Wuxi 9th People's Hospital Affiliated to Soochow University, Wuxi, China.
Jiang F; Department of Clinical Laboratory, Wuxi 9th People's Hospital Affiliated to Soochow University, Wuxi, China.
Zhao J; Department of Laboratory and Statistics, Shanghai QeeJen Bio-tech Institution, Shanghai, China.
Hu K; Department of Laboratory and Statistics, Shanghai QeeJen Bio-tech Institution, Shanghai, China.
Luo R; Department of Research Design, Shanghai QeeJen Bio-tech Institution, Shanghai, China.
Feng Y; Department of Research Design, Shanghai QeeJen Bio-tech Institution, Shanghai, China.
Lee H; Department of Bioengineering, Chonnam National University, Gwangju, South Korea.
Zhou D; Department of Rheumatology, The Royal Melbourne Hospital, Melbourne, VIC, Australia.
Mi J; Department of Research Design, Shanghai QeeJen Bio-tech Institution, Shanghai, China.
Deng R; Department of Sport Medicine, Wuxi 9th People's Hospital Affiliated to Soochow University, Wuxi, China.

Front Immunol ; 13: 913830, 2022.

Article em En | MEDLINE | ID: mdl-35967391

Assuntos

Artrite Reumatoide; Proteína de Translocação 1 do Linfoma de Tecido Linfoide Associado à Mucosa; NF-kappa B; Osteoartrite; Artrite Reumatoide/tratamento farmacológico; Artrite Reumatoide/genética; Artrite Reumatoide/imunologia; Diferenciação Celular; Humanos; Leucócitos Mononucleares/imunologia; Sistema de Sinalização das MAP Quinases/imunologia; Proteína de Translocação 1 do Linfoma de Tecido Linfoide Associado à Mucosa/genética; Proteína de Translocação 1 do Linfoma de Tecido Linfoide Associado à Mucosa/imunologia; NF-kappa B/genética; NF-kappa B/imunologia; Osteoartrite/metabolismo; Células Th17/imunologia; Células Th2/imunologia; Resultado do Tratamento

Palavras-chave

MALT1; NF-κB and JNK pathways; Th1/2/17 cells; rheumatoid arthritis; treatment outcome

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoartrite / Artrite Reumatoide / NF-kappa B / Proteína de Translocação 1 do Linfoma de Tecido Linfoide Associado à Mucosa Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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