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SILAC-based chemoproteomics reveals a neoligan analogue as an anti-inflammatory agent targeting IRGM to ameliorate cytokine storm.
Zhang, Jichao; Li, Yang; Meng, Guibing; Lu, Kui; Yan, Jiankun; Wu, Jiangpeng; Li, Pengyan; Luo, Lingling; Chen, Xi; Zhao, Xia; Qiu, Feng.
Afiliação
  • Zhang J; School of Chinese Materia Medica, and State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
  • Li Y; School of Chinese Materia Medica, and State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
  • Meng G; School of Chinese Materia Medica, and State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
  • Lu K; China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, College of Biotechnology, Tianjin University of Science & Technology, Tianjin, 300457, China.
  • Yan J; School of Chinese Materia Medica, and State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
  • Wu J; School of Chinese Materia Medica, and State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
  • Li P; School of Chinese Materia Medica, and State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
  • Luo L; School of Chinese Materia Medica, and State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
  • Chen X; School of Chinese Materia Medica, and State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China. Electronic address: Chenxi2014@tjutcm.edu.cn.
  • Zhao X; College of Chemistry, Tianjin Normal University, Tianjin, 300387, China. Electronic address: hxxyzhx@mail.tjnu.edu.cn.
  • Qiu F; School of Chinese Materia Medica, and State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China. Electronic address: fengqiu20070118@163.com.
Eur J Med Chem ; 241: 114659, 2022 Nov 05.
Article em En | MEDLINE | ID: mdl-35970074
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sepse / Proteínas de Ligação ao GTP / Síndrome da Liberação de Citocina / Anti-Inflamatórios Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sepse / Proteínas de Ligação ao GTP / Síndrome da Liberação de Citocina / Anti-Inflamatórios Idioma: En Ano de publicação: 2022 Tipo de documento: Article