Working correlates of protection predict SchuS4-derived-vaccine candidates with improved efficacy against an intracellular bacterium, Francisella tularensis.

De Pascalis, Roberto; Frey, Blake; Rice, Helen M; Bhargava, Varunika; Wu, Terry H; Peterson, Ross L; Conlan, J Wayne; Sjöstedt, Anders; Elkins, Karen L

De Pascalis, Roberto; Frey, Blake; Rice, Helen M; Bhargava, Varunika; Wu, Terry H; Peterson, Ross L; Conlan, J Wayne; Sjöstedt, Anders; Elkins, Karen L.

Afiliação

De Pascalis R; Laboratory of Mucosal Pathogens and Cellular Immunology, Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, USA. roberto.depascalis@fda.hhs.gov.
Frey B; Laboratory of Mucosal Pathogens and Cellular Immunology, Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, USA.
Rice HM; University of Alabama-Birmingham, Birmingham, AL, USA.
Bhargava V; Laboratory of Mucosal Pathogens and Cellular Immunology, Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, USA.
Wu TH; University of Bristol, Bristol, UK.
Peterson RL; Laboratory of Mucosal Pathogens and Cellular Immunology, Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, USA.
Conlan JW; Regeneron Pharmaceuticals, Tarrytown, NY, USA.
Sjöstedt A; Center for Infectious Disease and Immunity and Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA.
Elkins KL; Vaccine Evaluation Branch, Division of Biostatistics, Office of Biostatistics and Epidemiology, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, USA.

NPJ Vaccines ; 7(1): 95, 2022 Aug 17.

Article em En | MEDLINE | ID: mdl-35977964

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article