[Gender-associated differences in bladder cancer]. / Geschlechtsassoziierte Unterschiede beim Harnblasenkarzinom.
Urologie
; 61(10): 1060-1067, 2022 Oct.
Article
em De
| MEDLINE
| ID: mdl-35980439
ABSTRACT
BACKGROUND AND OBJECTIVES:
Although the incidence of bladder cancer among women is lower, they tend to more often have advanced disease at presentation with a more aggressive course. It is still unclear which factors are responsible for the poorer prognosis of bladder cancer in women. MATERIALS ANDMETHODS:
Original papers and reviews from 2004 until 2022 were identified in a PubMed search and evaluated.RESULTS:
Multiple factors are likely responsible for the different courses of bladder cancer in women versus men. In the literature, epidemiologic and clinical aspects are discussed. Furthermore, genetic and hormonal causes and the role of the urobiome have been the focus of discussion more recently.CONCLUSIONS:
Earlier diagnosis and better surgical treatment could lead to a more favorable course of bladder cancer in women. Further analyses of genetic, hormonal, und microbiological factors could open new perspectives in the prevention, diagnosis, and treatment of bladder cancer.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Bexiga Urinária
Idioma:
De
Ano de publicação:
2022
Tipo de documento:
Article