In situ single particle classification reveals distinct 60S maturation intermediates in cells.

Lucas, Bronwyn A; Zhang, Kexin; Loerch, Sarah; Grigorieff, Nikolaus

Lucas, Bronwyn A; Zhang, Kexin; Loerch, Sarah; Grigorieff, Nikolaus.

Afiliação

Lucas BA; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, United States.
Zhang K; Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, United States.
Loerch S; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, United States.
Grigorieff N; Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, United States.

Elife ; 112022 08 25.

Article em En | MEDLINE | ID: mdl-36005291

Assuntos

Proteínas de Saccharomyces cerevisiae; Microscopia Crioeletrônica/métodos; Funções Verossimilhança; Modelos Moleculares; Ribossomos; Saccharomyces cerevisiae

Palavras-chave

2DTM; FIB-milling; S. cerevisiae; cell biology; in situ cryo-EM; molecular biophysics; nucleus; particle classification; ribosome biogenesis; structural biology

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Saccharomyces cerevisiae Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Saccharomyces cerevisiae Idioma: En Ano de publicação: 2022 Tipo de documento: Article