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Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1.
Shin, Hijai R; Citron, Y Rose; Wang, Lei; Tribouillard, Laura; Goul, Claire S; Stipp, Robin; Sugasawa, Yusuke; Jain, Aakriti; Samson, Nolwenn; Lim, Chun-Yan; Davis, Oliver B; Castaneda-Carpio, David; Qian, Mingxing; Nomura, Daniel K; Perera, Rushika M; Park, Eunyong; Covey, Douglas F; Laplante, Mathieu; Evers, Alex S; Zoncu, Roberto.
Afiliação
  • Shin HR; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720, USA.
  • Citron YR; Innovative Genomics Initiative at the University of California, Berkeley, Berkeley, CA 94720, USA.
  • Wang L; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720, USA.
  • Tribouillard L; Innovative Genomics Initiative at the University of California, Berkeley, Berkeley, CA 94720, USA.
  • Goul CS; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Stipp R; Centre de recherche sur le cancer de l'Université Laval, Université Laval, Québec, QC G1R 3S3, Canada.
  • Sugasawa Y; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720, USA.
  • Jain A; Innovative Genomics Initiative at the University of California, Berkeley, Berkeley, CA 94720, USA.
  • Samson N; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720, USA.
  • Lim CY; Innovative Genomics Initiative at the University of California, Berkeley, Berkeley, CA 94720, USA.
  • Davis OB; Department of Anesthesiology and Pain Medicine, Juntendo University School of Medicine, Tokyo 113-8421, Japan.
  • Castaneda-Carpio D; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720, USA.
  • Qian M; Innovative Genomics Initiative at the University of California, Berkeley, Berkeley, CA 94720, USA.
  • Nomura DK; Centre de recherche sur le cancer de l'Université Laval, Université Laval, Québec, QC G1R 3S3, Canada.
  • Perera RM; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720, USA.
  • Park E; Innovative Genomics Initiative at the University of California, Berkeley, Berkeley, CA 94720, USA.
  • Covey DF; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720, USA.
  • Laplante M; Innovative Genomics Initiative at the University of California, Berkeley, Berkeley, CA 94720, USA.
  • Evers AS; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720, USA.
  • Zoncu R; Innovative Genomics Initiative at the University of California, Berkeley, Berkeley, CA 94720, USA.
Science ; 377(6612): 1290-1298, 2022 09 16.
Article em En | MEDLINE | ID: mdl-36007018
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colesterol / Receptores Acoplados a Proteínas G / Alvo Mecanístico do Complexo 1 de Rapamicina / Lisossomos Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colesterol / Receptores Acoplados a Proteínas G / Alvo Mecanístico do Complexo 1 de Rapamicina / Lisossomos Idioma: En Ano de publicação: 2022 Tipo de documento: Article