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Epigenetic regulation in intervertebral disc degeneration.
Li, Gaocai; Zhang, Weifeng; Liang, Huaizhen; Yang, Cao.
Afiliação
  • Li G; Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430022 Wuhan, China.
  • Zhang W; Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430022 Wuhan, China.
  • Liang H; Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430022 Wuhan, China.
  • Yang C; Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430022 Wuhan, China. Electronic address: caoyangunion@hust.edu.cn.
Trends Mol Med ; 28(10): 803-805, 2022 10.
Article em En | MEDLINE | ID: mdl-36030154
ABSTRACT
Intervertebral disc (IVD) degeneration is the leading cause of low back pain, which has a striking impact on numerous patients. Therefore, comprehensively illuminating the regulatory mechanisms of IVD degeneration is of great significance. Here, we discuss the latest advances in understanding the main epigenetic mechanisms regulating IVD degeneration.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Degeneração do Disco Intervertebral / Disco Intervertebral Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Degeneração do Disco Intervertebral / Disco Intervertebral Idioma: En Ano de publicação: 2022 Tipo de documento: Article