Therapeutic effect of fastigial nucleus stimulation is mediated by the microRNA-182 & microRNA-382/BDNF signaling pathways in the treatment of post-stroke depression.

Zhang, Zhuang; Xia, Dong-Jian; Xu, An-Ding

Zhang, Zhuang; Xia, Dong-Jian; Xu, An-Ding.

Afiliação

Zhang Z; Department of Neurology and Stroke Center, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, 510630, China; Department of Neurology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, 121001, China.
Xia DJ; Department of Neurosurgery, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, 121001, China.
Xu AD; Department of Neurology and Stroke Center, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, 510630, China. Electronic address: fsnxdjsd@yeah.net.

Biochem Biophys Res Commun ; 627: 137-145, 2022 10 30.

Article em En | MEDLINE | ID: mdl-36030655

Assuntos

MicroRNAs; Acidente Vascular Cerebral; Animais; Fator Neurotrófico Derivado do Encéfalo/metabolismo; Núcleos Cerebelares/metabolismo; Depressão/genética; Depressão/terapia; MicroRNAs/metabolismo; RNA Mensageiro/metabolismo; Ratos; Transdução de Sinais; Acidente Vascular Cerebral/tratamento farmacológico; Acidente Vascular Cerebral/terapia

Palavras-chave

Apoptosis; BDNF; Fastigial nucleus electrical stimulation (FN stimulation); Post stroke depression (PSD); miR-182; miR-382

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acidente Vascular Cerebral / MicroRNAs Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acidente Vascular Cerebral / MicroRNAs Idioma: En Ano de publicação: 2022 Tipo de documento: Article