Norcantharidin overcomes vemurafenib resistance in melanoma by inhibiting pentose phosphate pathway and lipogenesis <i>via</i> downregulating the mTOR pathway.

Wang, Lei; Otkur, Wuxiyar; Wang, Aman; Wang, Wen; Lyu, Yitong; Fang, Lei; Shan, Xiu; Song, Mingzhou; Feng, Yan; Zhao, Yi; Piao, Hai-Long; Qi, Huan; Liu, Ji-Wei

Norcantharidin overcomes vemurafenib resistance in melanoma by inhibiting pentose phosphate pathway and lipogenesis via downregulating the mTOR pathway.

Wang, Lei; Otkur, Wuxiyar; Wang, Aman; Wang, Wen; Lyu, Yitong; Fang, Lei; Shan, Xiu; Song, Mingzhou; Feng, Yan; Zhao, Yi; Piao, Hai-Long; Qi, Huan; Liu, Ji-Wei.

Afiliação

Wang L; Department of Oncology, First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, China.
Otkur W; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.
Wang A; Department of Geriatric Oncology, Dalian Friendship Hospital, Dalian, China.
Wang W; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.
Lyu Y; Department of Oncology, First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, China.
Fang L; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.
Shan X; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.
Song M; Department of Thoracic Surgery, Lung Cancer Diagnosis and Treatment Center of Dalian, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Feng Y; Department of Oncology, First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, China.
Zhao Y; Department of Computer Science, New Mexico State University, Las Cruces, NM, United States.
Piao HL; Graduate Program in Molecular Biology and Interdisciplinary Life Sciences, New Mexico State University, Las Cruces, NM, United States.
Qi H; Department of Geriatric Oncology, Dalian Friendship Hospital, Dalian, China.
Liu JW; Department of Oncology, First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, China.