Pharmacokinetic and pharmacodynamic profiles of a novel phospholipid-aspirin complex liquid formulation and low dose enteric-coated aspirin: results from a prospective, randomized, crossover study.

Franchi, Francesco; Schneider, David J; Prats, Jayne; Fan, Weihong; Rollini, Fabiana; Been, Latonya; Taatjes-Sommer, Heidi S; Bhatt, Deepak L; Deliargyris, Efthymios N; Angiolillo, Dominick J

Franchi, Francesco; Schneider, David J; Prats, Jayne; Fan, Weihong; Rollini, Fabiana; Been, Latonya; Taatjes-Sommer, Heidi S; Bhatt, Deepak L; Deliargyris, Efthymios N; Angiolillo, Dominick J.

Afiliação

Franchi F; Division of Cardiology, University of Florida College of Medicine - Jacksonville, 655 West 8th Street, Jacksonville, FL, 32209, USA.
Schneider DJ; Department of Medicine, Cardiovascular Research Institute, The University of Vermont, Burlington, VT, USA.
Prats J; Elysis LLC, Carlisle, MA, USA.
Fan W; PLx Pharma, Inc., Sparta, NJ, USA.
Rollini F; Division of Cardiology, University of Florida College of Medicine - Jacksonville, 655 West 8th Street, Jacksonville, FL, 32209, USA.
Been L; Division of Cardiology, University of Florida College of Medicine - Jacksonville, 655 West 8th Street, Jacksonville, FL, 32209, USA.
Taatjes-Sommer HS; Department of Medicine, Cardiovascular Research Institute, The University of Vermont, Burlington, VT, USA.
Bhatt DL; Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Deliargyris EN; Science and Strategy Consulting Group, Basking Ridge, NJ, USA.
Angiolillo DJ; Division of Cardiology, University of Florida College of Medicine - Jacksonville, 655 West 8th Street, Jacksonville, FL, 32209, USA. dominick.angiolillo@jax.ufl.edu.

J Thromb Thrombolysis ; 54(3): 373-381, 2022 Oct.

Article em En | MEDLINE | ID: mdl-36036856

Assuntos

Aspirina; Inibidores da Agregação Plaquetária; Ácido Araquidônico; Aspirina/farmacocinética; Aspirina/farmacologia; Cápsulas; Estudos Cross-Over; Humanos; Fosfolipídeos; Inibidores da Agregação Plaquetária/farmacocinética; Inibidores da Agregação Plaquetária/farmacologia; Estudos Prospectivos; Ácido Salicílico; Comprimidos; Tromboxano B2

Palavras-chave

Aspirin; PL-ASA; Pharmacodynamic; Pharmacokinetic; Platelet

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores da Agregação Plaquetária / Aspirina Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores da Agregação Plaquetária / Aspirina Idioma: En Ano de publicação: 2022 Tipo de documento: Article