Pore opening, not voltage sensor movement, underpins the voltage-dependence of facilitation by a hERG blocker.

Furutani, Kazuharu; Kawano, Ryotaro; Ichiwara, Minami; Adachi, Ryo; Clancy, Colleen E; Sack, Jon T; Kita, Satomi.

Afiliação

Furutani K; Department of Pharmacology, Tokushima Bunri University, Japan furutani@ph.bunri-u.ac.jp.
Kawano R; Department of Pharmacology, Tokushima Bunri University, Japan.
Ichiwara M; Department of Pharmacology, Tokushima Bunri University, Japan.
Adachi R; Department of Pharmacology, Tokushima Bunri University, Japan.
Clancy CE; UC Davis School of Medicine, United States.
Sack JT; UC Davis School of Medicine, United States.
Kita S; Department of Pharmacology, Tokushima Bunri University, Japan.

Mol Pharmacol ; 2022 Aug 30.

Article em En | MEDLINE | ID: mdl-36041862