Gestational age-based reference ranges for cervical length and preterm birth prediction in triplet pregnancies: an observational retrospective study.
BMC Pregnancy Childbirth
; 22(1): 669, 2022 Aug 30.
Article
em En
| MEDLINE
| ID: mdl-36042432
ABSTRACT
OBJECTIVES:
To develop gestational age-based reference ranges for cervical length in triplet pregnancies. The secondary objective was to assess the performance of cervical length measured between 18 and 20 + 6 days for the prediction of preterm delivery before 28 and 32 weeks, respectively.METHODS:
Observational retrospective study of triplet pregnancies in three Spanish tertiary-care hospitals between 2001 and 2019. Cervical length measurements were consecutively obtained between 15 and 34 weeks of gestation. Pregnancies undergoing multifetal reduction or fetal surgery were excluded.RESULTS:
Two hundred and six triplet pregnancies were included in the final analysis. There was a quadratic decrease in cervical length with gestational age. The median and fifth centiles for cervical length at 20 weeks were 35 and 13 mm. In the prediction of preterm birth < 28 weeks, for a false positive rate of 5%, and 10%, the detection rates were 40.9%, and 40.9%, respectively, and the prediction of preterm birth < 32 weeks, 22.0% and 26.0%, respectively.CONCLUSIONS:
In triplet pregnancies, cervical length decreases with gestational age. The performance of cervical length at 18-20 + 6 in screening for preterm birth before 28 and 32 weeks is poor.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Nascimento Prematuro
/
Gravidez de Trigêmeos
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article