Genome-wide CRISPR-Cas9 screen reveals a persistent null-hyphal phenotype that maintains high carotenoid production in Yarrowia lipolytica.

Lupish, Brian; Hall, Jordan; Schwartz, Cory; Ramesh, Adithya; Morrison, Clifford; Wheeldon, Ian

Lupish, Brian; Hall, Jordan; Schwartz, Cory; Ramesh, Adithya; Morrison, Clifford; Wheeldon, Ian.

Afiliação

Lupish B; Department of Bioengineering, University of California, Riverside, California, USA.
Hall J; Department of Chemical and Environmental Engineering, University of California, Riverside, California, USA.
Schwartz C; Department of Chemical and Environmental Engineering, University of California, Riverside, California, USA.
Ramesh A; Department of Chemical and Environmental Engineering, University of California, Riverside, California, USA.
Morrison C; Department of Chemical and Environmental Engineering, University of California, Riverside, California, USA.
Wheeldon I; Department of Chemical and Environmental Engineering, University of California, Riverside, California, USA.

Biotechnol Bioeng ; 119(12): 3623-3631, 2022 Dec.

Article em En | MEDLINE | ID: mdl-36042688

Assuntos

Yarrowia; Yarrowia/genética; Yarrowia/metabolismo; Hifas; Licopeno/metabolismo; Sistemas CRISPR-Cas; Engenharia Metabólica; Carotenoides/metabolismo; Fenótipo

Palavras-chave

RAS2; genetic screening; lycopene; metabolic engineering; nonconventional yeast

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Yarrowia Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Yarrowia Idioma: En Ano de publicação: 2022 Tipo de documento: Article