Presumptive isolated neurosarcoidosis involving eloquent structures: An argument for empirical TNF-α inhibition.
J Neuroimmunol
; 372: 577956, 2022 11 15.
Article
em En
| MEDLINE
| ID: mdl-36054936
ABSTRACT
There are clinical and radiological phenotypes characteristic of neurosarcoidosis. Histopathologic confirmation is preferred, however, biopsy is associated with a significant risk of morbidity when only eloquent neural structures are involved and where there is no systemic disease. We present a series of patients with isolated neurosarcoidosis and suggest circumstances where an empirical, closely monitored, trial of tumour-necrosis-factor-alpha inhibitor therapy can improve outcome and diagnostic confidence.
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Base de dados:
MEDLINE
Assunto principal:
Sarcoidose
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Doenças do Sistema Nervoso Central
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article