T-Cell Responses Against Mycobacterium ulcerans and Mycobacterium tuberculosis Protein Extracts Identify Children With Buruli Ulcer Disease.
J Pediatric Infect Dis Soc
; 11(12): 575-577, 2022 Dec 28.
Article
em En
| MEDLINE
| ID: mdl-36070406
ABSTRACT
Immune-based diagnosis of Buruli ulcer disease (BUD) in children is difficult due to cross-reactivity between mycobacteria. We found that T-cell IFNγ/TNFα responses against Mycobacterium (M.) ulcerans and M. tuberculosis (PPDMulc, PPDMtub) were different between children with BUD (nâ
=â
27) and TB (nâ
=â
20) but only ratios (PPDMtub/PPDMulc) discriminated the study groups efficiently.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Mycobacterium ulcerans
/
Úlcera de Buruli
/
Mycobacterium tuberculosis
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article