Ceramide induces macrophage migration inhibitory factor -mediated parthanatos in mouse neurons by increasing ROS levels.

Fan, Chenghe; Tian, Yu; Zhang, Yilin; Teng, Junfang; Zhao, Xinyu

Fan, Chenghe; Tian, Yu; Zhang, Yilin; Teng, Junfang; Zhao, Xinyu.

Afiliação

Fan C; Department of Neurology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi District, Zhengzhou 450052, China; Henan Medical College of Zhengzhou University, No.50 Zhongyuan Road, Erqi District, Zhengzhou 450052, China.
Tian Y; Department of Neurology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi District, Zhengzhou 450052, China; Henan Medical College of Zhengzhou University, No.50 Zhongyuan Road, Erqi District, Zhengzhou 450052, China.
Zhang Y; Department of Neurology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi District, Zhengzhou 450052, China; Henan Medical College of Zhengzhou University, No.50 Zhongyuan Road, Erqi District, Zhengzhou 450052, China.
Teng J; Department of Neurology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi District, Zhengzhou 450052, China; Henan Medical College of Zhengzhou University, No.50 Zhongyuan Road, Erqi District, Zhengzhou 450052, China; Department of Neurological Intensive Care Unit,
Zhao X; Department of Neurology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Erqi District, Zhengzhou 450052, China; Henan Medical College of Zhengzhou University, No.50 Zhongyuan Road, Erqi District, Zhengzhou 450052, China; Department of Neurological Intensive Care Unit,

Neurosci Lett ; 788: 136862, 2022 09 25.

Article em En | MEDLINE | ID: mdl-36075319

Assuntos

Fatores Inibidores da Migração de Macrófagos; Parthanatos; Animais; Fator de Indução de Apoptose/metabolismo; Ceramidas/metabolismo; Ceramidas/farmacologia; Fatores Inibidores da Migração de Macrófagos/metabolismo; Camundongos; Neurônios/metabolismo; Inibidores de Poli(ADP-Ribose) Polimerases; RNA Interferente Pequeno/farmacologia; Espécies Reativas de Oxigênio/metabolismo

Palavras-chave

Ceramide; MIF; PARP-1; Parthanatos; ROS

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores Inibidores da Migração de Macrófagos / Parthanatos Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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