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Chemoproteomics-Enabled Identification of 4-Oxo-ß-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.
Carvalho, Luís A R; Ross, Breyan; Fehr, Lorenz; Bolgi, Oguz; Wöhrle, Svenja; Lum, Kenneth M; Podlesainski, David; Vieira, Andreia C; Kiefersauer, Reiner; Félix, Rita; Rodrigues, Tiago; Lucas, Susana D; Groß, Olaf; Geiss-Friedlander, Ruth; Cravatt, Benjamin F; Huber, Robert; Kaiser, Markus; Moreira, Rui.
Afiliação
  • Carvalho LAR; Department of Pharmaceutical Sciences and Medicines, Research Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal.
  • Ross B; Department of Chemistry, The Scripps Research Institute, La Jolla, California, 92037, USA.
  • Fehr L; Max Planck Institut für Biochemie, 82152, PlaneggMartinsried, Germany.
  • Bolgi O; Proteros Biostructures GmbH, 82152, PlaneggMartinsried, Germany.
  • Wöhrle S; Fakultät für Biologie, Zentrum für Medizinische Biotechnologie, Universität Duisburg-Essen, 45117, Essen, Germany.
  • Lum KM; Center of Biochemistry and Molecular Cell Research, Albert-Ludwigs-Universität, 79104, Freiburg, Germany.
  • Podlesainski D; Institut für Neuropathologie, Universitätsklinikum Freiburg, 79106, Freiburg, Germany.
  • Vieira AC; Department of Chemistry, The Scripps Research Institute, La Jolla, California, 92037, USA.
  • Kiefersauer R; Fakultät für Biologie, Zentrum für Medizinische Biotechnologie, Universität Duisburg-Essen, 45117, Essen, Germany.
  • Félix R; Department of Pharmaceutical Sciences and Medicines, Research Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal.
  • Rodrigues T; Proteros Biostructures GmbH, 82152, PlaneggMartinsried, Germany.
  • Lucas SD; Department of Pharmaceutical Sciences and Medicines, Research Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal.
  • Groß O; Department of Pharmaceutical Sciences and Medicines, Research Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal.
  • Geiss-Friedlander R; Department of Pharmaceutical Sciences and Medicines, Research Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal.
  • Cravatt BF; Institut für Neuropathologie, Universitätsklinikum Freiburg, 79106, Freiburg, Germany.
  • Huber R; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, 79104, Freiburg, Germany.
  • Kaiser M; Center of Biochemistry and Molecular Cell Research, Albert-Ludwigs-Universität, 79104, Freiburg, Germany.
  • Moreira R; Department of Chemistry, The Scripps Research Institute, La Jolla, California, 92037, USA.
Angew Chem Int Ed Engl ; 61(47): e202210498, 2022 11 21.
Article em En | MEDLINE | ID: mdl-36089535
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dipeptidases Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dipeptidases Idioma: En Ano de publicação: 2022 Tipo de documento: Article