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Selective targeting of GARP-LTGFß axis in the tumor microenvironment augments PD-1 blockade via enhancing CD8+ T cell antitumor immunity.
Li, Anqi; Chang, Yuzhou; Song, No-Joon; Wu, Xingjun; Chung, Dongjun; Riesenberg, Brian P; Velegraki, Maria; Giuliani, Giuseppe D; Das, Komal; Okimoto, Tamio; Kwon, Hyunwoo; Chakravarthy, Karthik B; Bolyard, Chelsea; Wang, Yi; He, Kai; Gatti-Mays, Margaret; Das, Jayajit; Yang, Yiping; Gewirth, Daniel T; Ma, Qin; Carbone, David; Li, Zihai.
Afiliação
  • Li A; College of Medicine, The Ohio State University, Columbus, Ohio, USA.
  • Chang Y; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G James Cancer Hospital and Richard J Solove Research Institute, The Ohio State University, Columbus, Ohio, USA.
  • Song NJ; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G James Cancer Hospital and Richard J Solove Research Institute, The Ohio State University, Columbus, Ohio, USA.
  • Wu X; Department of Biomedical Informatics, The Ohio State University College of Medicine, Columbus, Ohio, USA.
  • Chung D; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G James Cancer Hospital and Richard J Solove Research Institute, The Ohio State University, Columbus, Ohio, USA.
  • Riesenberg BP; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G James Cancer Hospital and Richard J Solove Research Institute, The Ohio State University, Columbus, Ohio, USA.
  • Velegraki M; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G James Cancer Hospital and Richard J Solove Research Institute, The Ohio State University, Columbus, Ohio, USA.
  • Giuliani GD; Department of Biomedical Informatics, The Ohio State University College of Medicine, Columbus, Ohio, USA.
  • Das K; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G James Cancer Hospital and Richard J Solove Research Institute, The Ohio State University, Columbus, Ohio, USA.
  • Okimoto T; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G James Cancer Hospital and Richard J Solove Research Institute, The Ohio State University, Columbus, Ohio, USA.
  • Kwon H; Battelle Center for Mathematical Medicine, The Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, Ohio, USA.
  • Chakravarthy KB; Department of Physics, The Ohio State University, Columbus, Ohio, USA.
  • Bolyard C; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G James Cancer Hospital and Richard J Solove Research Institute, The Ohio State University, Columbus, Ohio, USA.
  • Wang Y; College of Medicine, The Ohio State University, Columbus, Ohio, USA.
  • He K; College of Medicine, The Ohio State University, Columbus, Ohio, USA.
  • Gatti-Mays M; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G James Cancer Hospital and Richard J Solove Research Institute, The Ohio State University, Columbus, Ohio, USA.
  • Das J; College of Medicine, The Ohio State University, Columbus, Ohio, USA.
  • Yang Y; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G James Cancer Hospital and Richard J Solove Research Institute, The Ohio State University, Columbus, Ohio, USA.
  • Gewirth DT; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G James Cancer Hospital and Richard J Solove Research Institute, The Ohio State University, Columbus, Ohio, USA.
  • Ma Q; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G James Cancer Hospital and Richard J Solove Research Institute, The Ohio State University, Columbus, Ohio, USA.
  • Carbone D; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G James Cancer Hospital and Richard J Solove Research Institute, The Ohio State University, Columbus, Ohio, USA.
  • Li Z; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, Ohio, USA.
J Immunother Cancer ; 10(9)2022 09.
Article em En | MEDLINE | ID: mdl-36096533

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Microambiente Tumoral / Neoplasias Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Microambiente Tumoral / Neoplasias Idioma: En Ano de publicação: 2022 Tipo de documento: Article