Synaptic tagging: homeostatic plasticity goes Hebbian.
EMBO J
; 41(20): e112383, 2022 10 17.
Article
em En
| MEDLINE
| ID: mdl-36097740
ABSTRACT
Distinct plasticity mechanisms enable neurons to effectively process information also when facing global perturbations in network activity. In this issue of The EMBO Journal, Dubes et al (2022) provide a molecular mechanism whereby individual synapses during periods of chronic inactivity are "tagged" for future strengthening. These results lend further support to the idea that local, nonmultiplicative mechanisms play an important role in homeostatic synaptic plasticity as has been demonstrated for Hebbian-like synaptic plasticity.
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Base de dados:
MEDLINE
Assunto principal:
Sinapses
/
Plasticidade Neuronal
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article