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Blood pressure-independent renoprotective effects of small interference RNA targeting liver angiotensinogen in experimental diabetes.
Cruz-López, Edwyn O; Ren, Liwei; Uijl, Estrellita; Clahsen-van Groningen, Marian C; van Veghel, Richard; Garrelds, Ingrid M; Domenig, Oliver; Poglitsch, Marko; Zlatev, Ivan; Rooney, Timothy; Kasper, Anne; Nioi, Paul; Foster, Don; Danser, A H Jan.
Afiliação
  • Cruz-López EO; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.
  • Ren L; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.
  • Uijl E; Department of Pharmacy, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, China.
  • Clahsen-van Groningen MC; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.
  • van Veghel R; Division of Nephrology and Transplantation, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.
  • Garrelds IM; Department of Pathology, Erasmus MC, Rotterdam, The Netherlands.
  • Domenig O; Institute of Experimental Medicine and Systems Biology, University Hospital Aachen, RWTH Aachen University, Aachen, Germany.
  • Poglitsch M; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.
  • Zlatev I; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.
  • Rooney T; Attoquant Diagnostics, Vienna, Austria.
  • Kasper A; Attoquant Diagnostics, Vienna, Austria.
  • Nioi P; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
  • Foster D; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
  • Danser AHJ; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
Br J Pharmacol ; 180(1): 80-93, 2023 Jan.
Article em En | MEDLINE | ID: mdl-36106615

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Angiotensina II / RNA Interferente Pequeno / Diabetes Mellitus Experimental / Hipertensão / Nefropatias Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Angiotensina II / RNA Interferente Pequeno / Diabetes Mellitus Experimental / Hipertensão / Nefropatias Idioma: En Ano de publicação: 2023 Tipo de documento: Article