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Haploinsufficiency of CYP8B1 associates with increased insulin sensitivity in humans.
Zhong, Shiqi; Chèvre, Raphael; Castaño Mayan, David; Corlianò, Maria; Cochran, Blake J; Sem, Kai Ping; van Dijk, Theo H; Peng, Jianhe; Tan, Liang Juin; Hartimath, Siddesh V; Ramasamy, Boominathan; Cheng, Peter; Groen, Albert K; Kuipers, Folkert; Goggi, Julian L; Drum, Chester; van Dam, Rob M; Tan, Ru San; Rye, Kerry-Anne; Hayden, Michael R; Cheng, Ching-Yu; Chacko, Shaji; Flannick, Jason; Sim, Xueling; Tan, Hong Chang; Singaraja, Roshni R.
Afiliação
  • Zhong S; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Chèvre R; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research (A*STAR), Singapore.
  • Castaño Mayan D; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research (A*STAR), Singapore.
  • Corlianò M; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Cochran BJ; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research (A*STAR), Singapore.
  • Sem KP; Cardiovascular Research Institute, National University Health System, Singapore.
  • van Dijk TH; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Peng J; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research (A*STAR), Singapore.
  • Tan LJ; Cardiovascular Research Institute, National University Health System, Singapore.
  • Hartimath SV; School of Medical Sciences, University of New South Wales, Sydney, Australia.
  • Ramasamy B; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research (A*STAR), Singapore.
  • Cheng P; Departments of Pediatrics and Laboratory Medicine, University of Groningen, University Medical Center Groningen, Netherlands.
  • Groen AK; Experimental Therapeutics Centre and.
  • Kuipers F; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research (A*STAR), Singapore.
  • Goggi JL; Singapore Bioimaging Consortium, A*STAR, Singapore.
  • Drum C; Singapore Bioimaging Consortium, A*STAR, Singapore.
  • van Dam RM; Singapore Bioimaging Consortium, A*STAR, Singapore.
  • Tan RS; Departments of Pediatrics and Laboratory Medicine, University of Groningen, University Medical Center Groningen, Netherlands.
  • Rye KA; Departments of Pediatrics and Laboratory Medicine, University of Groningen, University Medical Center Groningen, Netherlands.
  • Hayden MR; Singapore Bioimaging Consortium, A*STAR, Singapore.
  • Cheng CY; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Chacko S; Cardiovascular Research Institute, National University Health System, Singapore.
  • Flannick J; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.
  • Sim X; Department of Cardiology, National Heart Centre, Singapore.
  • Tan HC; School of Medical Sciences, University of New South Wales, Sydney, Australia.
  • Singaraja RR; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, The University of British Columbia, Vancouver, British Columbia, Canada.
J Clin Invest ; 132(21)2022 11 01.
Article em En | MEDLINE | ID: mdl-36107630

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Esteroide 12-alfa-Hidroxilase Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Esteroide 12-alfa-Hidroxilase Idioma: En Ano de publicação: 2022 Tipo de documento: Article