Neutrophil chemotaxis in sickle cell anaemia, sickle cell beta zero thalassaemia, and after splenectomy.
J Clin Pathol
; 40(6): 670-2, 1987 Jun.
Article
em En
| MEDLINE
| ID: mdl-3611395
ABSTRACT
Neutrophil chemotaxis was evaluated in 28 patients with sickle cell anaemia, 10 patient with sickle cell beta zero thalassaemia, 25 patients who had undergone splenectomy, and 38 controls. The mean distance migrated by patients' neutrophils was not significantly different from that of neutrophils from controls. Although several immunological variables have been reported to be changed after loss of splenic function, we were unable to show a defect in neutrophil chemotaxis that could account for the increased susceptibility to infection.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Talassemia
/
Quimiotaxia de Leucócito
/
Anemia Falciforme
Idioma:
En
Ano de publicação:
1987
Tipo de documento:
Article