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Analysis of rare disruptive germline mutations in 2135 enriched BRCA-negative breast cancers excludes additional high-impact susceptibility genes.
Loveday, C; Garrett, A; Law, P; Hanks, S; Poyastro-Pearson, E; Adlard, J W; Barwell, J; Berg, J; Brady, A F; Brewer, C; Chapman, C; Cook, J; Davidson, R; Donaldson, A; Douglas, F; Greenhalgh, L; Henderson, A; Izatt, L; Kumar, A; Lalloo, F; Miedzybrodzka, Z; Morrison, P J; Paterson, J; Porteous, M; Rogers, M T; Walker, L; Eccles, D; Evans, D G; Snape, K; Hanson, H; Houlston, R S; Turnbull, C.
Afiliação
  • Loveday C; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
  • Garrett A; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
  • Law P; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
  • Hanks S; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
  • Poyastro-Pearson E; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
  • Adlard JW; Yorkshire Regional Genetics Service, St James's University Hospital, Leeds, UK.
  • Barwell J; Leicestershire Genetics Centre, University Hospitals of Leicester National Health Service (NHS) Trust, Leicester, UK.
  • Berg J; Division of Medical Sciences, Human Genetics, University of Dundee, Dundee, UK.
  • Brady AF; North West Thames Regional Genetics Service, Kennedy Galton Centre, London, UK.
  • Brewer C; Peninsula Regional Genetics Service, Royal Devon & Exeter Hospital, Exeter, UK.
  • Chapman C; West Midlands Regional Genetics Service, Birmingham Women's Hospital, Birmingham, UK.
  • Cook J; Sheffield Regional Genetics Service, Sheffield Children's NHS Foundation Trust, Sheffield, UK.
  • Davidson R; West of Scotland Regional Genetics Service, Ferguson Smith Centre for Clinical Genetics, Glasgow, UK.
  • Donaldson A; South Western Regional Genetics Service, University Hospitals of Bristol NHS Foundation Trust, Bristol, UK.
  • Douglas F; Northern Genetics Service, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
  • Greenhalgh L; Cheshire and Merseyside Clinical Genetics Service, Alder Hey Children's NHS Foundation Trust, Liverpool, UK.
  • Henderson A; Northern Genetics Service (Cumbria), Newcastle upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, UK.
  • Izatt L; South East Thames Regional Genetics Service, Guy's and St. Thomas NHS Foundation Trust, London, UK.
  • Kumar A; North East Thames Regional Genetics Service, Great Ormond St. Hospital, London, UK.
  • Lalloo F; University Department of Medical Genetics & Regional Genetics Service, St. Mary's Hospital, Manchester, UK.
  • Miedzybrodzka Z; University of Aberdeen and North of Scotland Clinical Genetics Service, Aberdeen Royal Infirmary, Aberdeen, UK.
  • Morrison PJ; Belfast Health and Social Care (HSC) Trust & Department of Medical Genetics, Northern Ireland Regional Genetics Service, Queen's University Belfast, Belfast, UK.
  • Paterson J; East Anglian Regional Genetics Service, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  • Porteous M; South East of Scotland Clinical Genetics Service, Western General Hospital, Edinburgh, UK.
  • Rogers MT; All Wales Medical Genetics Service, University Hospital of Wales, Cardiff, UK.
  • Walker L; Oxford Regional Genetics Service, Oxford Radcliffe Hospitals NHS Trust, Oxford, UK.
  • Eccles D; Faculty of Medicine, University of Southampton, Southampton University Hospitals NHS Trust, Southampton, UK.
  • Evans DG; University Department of Medical Genetics & Regional Genetics Service, St. Mary's Hospital, Manchester, UK.
  • Snape K; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK; South West Thames Regional Genetics Service, St. George's Hospital, London, UK.
  • Hanson H; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK; South West Thames Regional Genetics Service, St. George's Hospital, London, UK.
  • Houlston RS; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
  • Turnbull C; Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK; Royal Marsden NHS Foundation Hospital, London, UK. Electronic address: clare.turnbull@icr.ac.uk.
Ann Oncol ; 33(12): 1318-1327, 2022 12.
Article em En | MEDLINE | ID: mdl-36122798
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Neoplasias da Mama / Neoplasias de Mama Triplo Negativas Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Neoplasias da Mama / Neoplasias de Mama Triplo Negativas Idioma: En Ano de publicação: 2022 Tipo de documento: Article