Wound-Induced Hair Neogenesis: A Portal to the Development of New Therapies for Hair Loss and Wound Regeneration.
Cold Spring Harb Perspect Biol
; 15(2)2023 02 01.
Article
em En
| MEDLINE
| ID: mdl-36123030
ABSTRACT
Adult mammals retain the remarkable ability to regenerate hair follicles after wounding. Wound-induced hair neogenesis (WIHN) in many ways recapitulates embryogenesis. The origin of the stem cells that give rise to a nascent hair follicle after wounding and the role of mesenchymal cells and signaling pathways responsible for this regenerative phenomenon are slowly being elucidated. WIHN provides a potential therapeutic window for manipulating cell fate by the introduction of factors during the wound healing process to enhance hair follicle formation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pele
/
Cabelo
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article