Membranolytic Mechanism of Amphiphilic Antimicrobial ß-Stranded [KL]<sub>n</sub> Peptides.

Membranolytic Mechanism of Amphiphilic Antimicrobial ß-Stranded [KL]_n Peptides.

Schweigardt, Fabian; Strandberg, Erik; Wadhwani, Parvesh; Reichert, Johannes; Bürck, Jochen; Cravo, Haroldo L P; Burger, Luisa; Ulrich, Anne S.

Afiliação

Schweigardt F; Karlsruhe Institute of Technology (KIT), Institute of Organic Chemistry, Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany.
Strandberg E; KIT, Institute of Biological Interfaces (IBG-2), P.O. Box 3640, 76021 Karlsruhe, Germany.
Wadhwani P; KIT, Institute of Biological Interfaces (IBG-2), P.O. Box 3640, 76021 Karlsruhe, Germany.
Reichert J; KIT, Institute of Biological Interfaces (IBG-2), P.O. Box 3640, 76021 Karlsruhe, Germany.
Bürck J; KIT, Institute of Biological Interfaces (IBG-2), P.O. Box 3640, 76021 Karlsruhe, Germany.
Cravo HLP; Laboratório de Biofísica Molecular, Universidade de São Paulo, Ribeirão Preto 14040-901, SP, Brazil.
Burger L; KIT, Institute of Biological Interfaces (IBG-2), P.O. Box 3640, 76021 Karlsruhe, Germany.
Ulrich AS; Karlsruhe Institute of Technology (KIT), Institute of Organic Chemistry, Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany.

Biomedicines ; 10(9)2022 Aug 24.

Article em En | MEDLINE | ID: mdl-36140173

Palavras-chave

antimicrobial activity; cationic antimicrobial peptides; hemolysis; length dependent activity; solid-state 31P-, 15N- and 19F-NMR; structure and orientation of peptides in membranes; vesicle leakage; ß-sheets; ß-stranded peptides

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article