Paired Box Gene 6 Regulates Heme Oxygenase-1 Expression and Mitigates Hydrogen Peroxide-Induced Oxidative Stress in Lens Epithelial Cells.

Zheng, Yuxing; Yang, Xiaoxi; Wu, Shuduan; Yi, Guoguo; Huang, Xiaobo; Feng, Zhizhen; Qu, Lei; Liu, Linyu; Li, Qianyun; Xia, Zhaoxia

Zheng, Yuxing; Yang, Xiaoxi; Wu, Shuduan; Yi, Guoguo; Huang, Xiaobo; Feng, Zhizhen; Qu, Lei; Liu, Linyu; Li, Qianyun; Xia, Zhaoxia.

Afiliação

Zheng Y; Department of Ophthalmology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yang X; Department of Ophthalmology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Wu S; Department of Ophthalmology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yi G; Department of Ophthalmology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Huang X; Department of Ophthalmology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Feng Z; Department of Ophthalmology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Qu L; Department of Ophthalmology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Liu L; Department of Ophthalmology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Li Q; Department of Ophthalmology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Xia Z; Department of Ophthalmology, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Curr Eye Res ; 47(11): 1516-1524, 2022 11.

Article em En | MEDLINE | ID: mdl-36149046

Assuntos

Peróxido de Hidrogênio; Cristalino; Animais; Anexina A5/metabolismo; Antioxidantes/metabolismo; Apoptose; Cápsulas/metabolismo; Células Epiteliais/metabolismo; Fluoresceínas/metabolismo; Heme Oxigenase-1/genética; Heme Oxigenase-1/metabolismo; Peróxido de Hidrogênio/metabolismo; Isotiocianatos; Cristalino/metabolismo; Proteínas de Membrana; Camundongos; Estresse Oxidativo; Fator de Transcrição PAX6; Propídio/metabolismo; RNA Interferente Pequeno/genética; Espécies Reativas de Oxigênio/metabolismo; Superóxido Dismutase/genética; Superóxido Dismutase/metabolismo

Palavras-chave

Age-related cataract; heme oxygenase-1; lens epithelial cells (SRA01/04 HLE-B3); oxidative stress; paired box gene 6

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peróxido de Hidrogênio / Cristalino Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peróxido de Hidrogênio / Cristalino Idioma: En Ano de publicação: 2022 Tipo de documento: Article