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Discovery of biphenyls bearing thiobarbiturate fragment by structure-based strategy as Mycobacterium tuberculosis protein tyrosine phosphatase B inhibitors.
Cheng, Shihao; Wang, Qinglin; Chen, Xi; Chen, Jiahao; Wang, Bin; Chen, Dongni; Shen, Dong; Tian, Jinying; Ye, Fei; Lu, Yu; Huang, Haihong; Lu, Yongjun; Zhang, Dongfeng.
Afiliação
  • Cheng S; Beijing Key Laboratory of Active Substance Discovery and Druggability Evaluation, Chinese Academy of Medical Sciences Key Laboratory of Anti-DR TB Innovative Drug Research, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beij
  • Wang Q; School of Life Sciences, Sun Yat-sen University, 135 West Xingang Road, Guangzhou, Guangdong 510275, PR China.
  • Chen X; Beijing Key Laboratory of Drug Resistance Tuberculosis Research, Department of Pharmacology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, 97 Ma Chang Street, Beijing 101149, PR China.
  • Chen J; School of Life Sciences, Sun Yat-sen University, 135 West Xingang Road, Guangzhou, Guangdong 510275, PR China.
  • Wang B; Beijing Key Laboratory of Drug Resistance Tuberculosis Research, Department of Pharmacology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, 97 Ma Chang Street, Beijing 101149, PR China.
  • Chen D; School of Life Sciences, Sun Yat-sen University, 135 West Xingang Road, Guangzhou, Guangdong 510275, PR China.
  • Shen D; School of Life Sciences, Sun Yat-sen University, 135 West Xingang Road, Guangzhou, Guangdong 510275, PR China.
  • Tian J; Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing 100050, PR China.
  • Ye F; Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing 100050, PR China.
  • Lu Y; Beijing Key Laboratory of Drug Resistance Tuberculosis Research, Department of Pharmacology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, 97 Ma Chang Street, Beijing 101149, PR China.
  • Huang H; Beijing Key Laboratory of Active Substance Discovery and Druggability Evaluation, Chinese Academy of Medical Sciences Key Laboratory of Anti-DR TB Innovative Drug Research, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beij
  • Lu Y; School of Life Sciences, Sun Yat-sen University, 135 West Xingang Road, Guangzhou, Guangdong 510275, PR China. Electronic address: luyj@mail.sysu.edu.cn.
  • Zhang D; Beijing Key Laboratory of Active Substance Discovery and Druggability Evaluation, Chinese Academy of Medical Sciences Key Laboratory of Anti-DR TB Innovative Drug Research, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beij
Bioorg Med Chem ; 73: 117006, 2022 11 01.
Article em En | MEDLINE | ID: mdl-36150342
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tuberculose / Mycobacterium tuberculosis Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tuberculose / Mycobacterium tuberculosis Idioma: En Ano de publicação: 2022 Tipo de documento: Article