Protocol of the TREASURE study: Thoracic RadiothErapy with Atezolizumab in Small cell lUng canceR Extensive disease - a randomized, open-label, multicenter phase II trial.

Bozorgmehr, Farastuk; Christopoulos, Petros; Chung, Inn; Cvetkovic, Jelena; Feißt, Manuel; Krisam, Johannes; Schneider, Marc A; Heußel, Claus Peter; Kreuter, Michael; Müller, Daniel W; Thomas, Michael; Rieken, Stefan

Bozorgmehr, Farastuk; Christopoulos, Petros; Chung, Inn; Cvetkovic, Jelena; Feißt, Manuel; Krisam, Johannes; Schneider, Marc A; Heußel, Claus Peter; Kreuter, Michael; Müller, Daniel W; Thomas, Michael; Rieken, Stefan.

Afiliação

Bozorgmehr F; Department of Thoracic Oncology, Thoraxklinik at University Hospital of Heidelberg, Röntgenstraße 1, 69126, Heidelberg, Germany. Farastuk.Bozorgmehr@med.uni-heidelberg.de.
Christopoulos P; Translational Lung Research Center Heidelberg TLRCH, Member of the German Center for Lung Research DZL, Im Neuenheimer Feld 156, 69120, Heidelberg, Germany. Farastuk.Bozorgmehr@med.uni-heidelberg.de.
Chung I; Department of Thoracic Oncology, Thoraxklinik at University Hospital of Heidelberg, Röntgenstraße 1, 69126, Heidelberg, Germany.
Cvetkovic J; Translational Lung Research Center Heidelberg TLRCH, Member of the German Center for Lung Research DZL, Im Neuenheimer Feld 156, 69120, Heidelberg, Germany.
Feißt M; Department of Thoracic Oncology, Thoraxklinik at University Hospital of Heidelberg, Röntgenstraße 1, 69126, Heidelberg, Germany.
Krisam J; Translational Lung Research Center Heidelberg TLRCH, Member of the German Center for Lung Research DZL, Im Neuenheimer Feld 156, 69120, Heidelberg, Germany.
Schneider MA; Department of Thoracic Oncology, Thoraxklinik at University Hospital of Heidelberg, Röntgenstraße 1, 69126, Heidelberg, Germany.
Heußel CP; Translational Lung Research Center Heidelberg TLRCH, Member of the German Center for Lung Research DZL, Im Neuenheimer Feld 156, 69120, Heidelberg, Germany.
Kreuter M; University Hospital of Heidelberg, Institute of Medical Biometry, Im Neuenheimer Feld 130.3, 69120, Heidelberg, Germany.
Müller DW; University Hospital of Heidelberg, Institute of Medical Biometry, Im Neuenheimer Feld 130.3, 69120, Heidelberg, Germany.
Thomas M; Translational Lung Research Center Heidelberg TLRCH, Member of the German Center for Lung Research DZL, Im Neuenheimer Feld 156, 69120, Heidelberg, Germany.
Rieken S; Thoraxklinik at University Hospital of Heidelberg, Translational Research Unit (STF), Röntgenstraße 1, 69126, Heidelberg, Germany.

BMC Cancer ; 22(1): 1011, 2022 Sep 24.

Article em En | MEDLINE | ID: mdl-36153496

Assuntos

Neoplasias Pulmonares; Carcinoma de Pequenas Células do Pulmão; Anticorpos Monoclonais Humanizados; Protocolos de Quimioterapia Combinada Antineoplásica/efeitos adversos; Antígeno B7-H1; Materiais Biocompatíveis/uso terapêutico; Ensaios Clínicos Fase II como Assunto; Humanos; Neoplasias Pulmonares/tratamento farmacológico; Neoplasias Pulmonares/radioterapia; Estudos Multicêntricos como Assunto; Ensaios Clínicos Controlados Aleatórios como Assunto; Carcinoma de Pequenas Células do Pulmão/tratamento farmacológico; Carcinoma de Pequenas Células do Pulmão/radioterapia

Palavras-chave

Anti-PD-L1 monoclonal antibody; Atezolizumab; Extensive disease small cell lung cancer; First-line therapy; Radioimmuntherapy; SCLC; Thoracic radiotherapy

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma de Pequenas Células do Pulmão / Neoplasias Pulmonares Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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