Sensitization to Ionizing Radiation by MEK Inhibition Is Dependent on SNAI2 in Fusion-Negative Rhabdomyosarcoma.

Hensch, Nicole R; Bondra, Kathryn; Wang, Long; Sreenivas, Prethish; Zhao, Xiang R; Modi, Paulomi; Vaseva, Angelina V; Houghton, Peter J; Ignatius, Myron S

Hensch, Nicole R; Bondra, Kathryn; Wang, Long; Sreenivas, Prethish; Zhao, Xiang R; Modi, Paulomi; Vaseva, Angelina V; Houghton, Peter J; Ignatius, Myron S.

Afiliação

Hensch NR; Greehey Children's Cancer Research Institute (GCCRI), Department of Molecular Medicine, UT Health Sciences Center, San Antonio, Texas.
Bondra K; Greehey Children's Cancer Research Institute (GCCRI), Department of Molecular Medicine, UT Health Sciences Center, San Antonio, Texas.
Wang L; Greehey Children's Cancer Research Institute (GCCRI), Department of Molecular Medicine, UT Health Sciences Center, San Antonio, Texas.
Sreenivas P; Greehey Children's Cancer Research Institute (GCCRI), Department of Molecular Medicine, UT Health Sciences Center, San Antonio, Texas.
Zhao XR; Greehey Children's Cancer Research Institute (GCCRI), Department of Molecular Medicine, UT Health Sciences Center, San Antonio, Texas.
Modi P; Greehey Children's Cancer Research Institute (GCCRI), Department of Molecular Medicine, UT Health Sciences Center, San Antonio, Texas.
Vaseva AV; Greehey Children's Cancer Research Institute (GCCRI), Department of Molecular Medicine, UT Health Sciences Center, San Antonio, Texas.
Houghton PJ; Greehey Children's Cancer Research Institute (GCCRI), Department of Molecular Medicine, UT Health Sciences Center, San Antonio, Texas.
Ignatius MS; Greehey Children's Cancer Research Institute (GCCRI), Department of Molecular Medicine, UT Health Sciences Center, San Antonio, Texas.

Mol Cancer Ther ; 22(1): 123-134, 2023 01 03.

Article em En | MEDLINE | ID: mdl-36162055

Assuntos

Rabdomiossarcoma; Criança; Humanos; Rabdomiossarcoma/tratamento farmacológico; Rabdomiossarcoma/genética; Rabdomiossarcoma/radioterapia; Diferenciação Celular; Inibidores de Proteínas Quinases/farmacologia; Transdução de Sinais; Quinases de Proteína Quinase Ativadas por Mitógeno; Linhagem Celular Tumoral; Fatores de Transcrição da Família Snail

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rabdomiossarcoma Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rabdomiossarcoma Idioma: En Ano de publicação: 2023 Tipo de documento: Article