Energetics of Spike Protein Opening of SARS-CoV-1 and SARS-CoV-2 and Its Variants of Concern: Implications in Host Receptor Scanning and Transmission.

Singh, Jasdeep; Vashishtha, Shubham; Rahman, Syed Asad; Ehtesham, Nasreen Zafar; Alam, Anwar; Kundu, Bishwajit; Dobrindt, Ulrich

Singh, Jasdeep; Vashishtha, Shubham; Rahman, Syed Asad; Ehtesham, Nasreen Zafar; Alam, Anwar; Kundu, Bishwajit; Dobrindt, Ulrich.

Afiliação

Singh J; Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology-Delhi, Hauz Khas, New Delhi 110016, India.
Vashishtha S; Kusuma School of Biological Sciences, Indian Institute of Technology-Delhi, Hauz Khas, New Delhi 110016, India.
Rahman SA; BioInception Pvt. Ltd., Future Business Centre, Kings Hedges Road, Cambridge CB4 2HY, U.K.
Ehtesham NZ; ICMR National Institute of Pathology, Safdarjung Hospital Campus, New Delhi 110029, India.
Alam A; ICMR National Institute of Pathology, Safdarjung Hospital Campus, New Delhi 110029, India.
Kundu B; Kusuma School of Biological Sciences, Indian Institute of Technology-Delhi, Hauz Khas, New Delhi 110016, India.
Dobrindt U; Institute of Hygiene, University of Münster, Münster 48149, Germany.

Biochemistry ; 61(20): 2188-2197, 2022 10 18.

Article em En | MEDLINE | ID: mdl-36166360

Assuntos

SARS-CoV-2; Glicoproteína da Espícula de Coronavírus; Humanos; Aminoácidos/metabolismo; Enzima de Conversão de Angiotensina 2/genética; Sítios de Ligação; COVID-19/genética; Mutação; Peptidil Dipeptidase A/química; Peptidil Dipeptidase A/genética; Peptidil Dipeptidase A/metabolismo; Ligação Proteica; SARS-CoV-2/genética; Glicoproteína da Espícula de Coronavírus/química

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicoproteína da Espícula de Coronavírus / SARS-CoV-2 Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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