Neurogenesis is disrupted in human hippocampal progenitor cells upon exposure to serum samples from hospitalized COVID-19 patients with neurological symptoms.

Borsini, Alessandra; Merrick, Blair; Edgeworth, Jonathan; Mandal, Gargi; Srivastava, Deepak P; Vernon, Anthony C; Nebbia, Gaia; Thuret, Sandrine; Pariante, Carmine M

Borsini, Alessandra; Merrick, Blair; Edgeworth, Jonathan; Mandal, Gargi; Srivastava, Deepak P; Vernon, Anthony C; Nebbia, Gaia; Thuret, Sandrine; Pariante, Carmine M.

Afiliação

Borsini A; Stress, Psychiatry and Immunology Laboratory, Institute of Psychiatry, Psychology and Neuroscience, Department of Psychological Medicine, King's College London, London, UK. alessandra.borsini@kcl.ac.uk.
Merrick B; Centre for Clinical Infection and Diagnostics Research, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Edgeworth J; School of Immunology and Microbial Sciences, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Mandal G; Stress, Psychiatry and Immunology Laboratory, Institute of Psychiatry, Psychology and Neuroscience, Department of Psychological Medicine, King's College London, London, UK.
Srivastava DP; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Vernon AC; MRC Centre for Neurodevelopmental Disorders, King's College London, London, UK.
Nebbia G; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Thuret S; MRC Centre for Neurodevelopmental Disorders, King's College London, London, UK.
Pariante CM; School of Immunology and Microbial Sciences, Guy's and St Thomas' NHS Foundation Trust, London, UK.

Mol Psychiatry ; 27(12): 5049-5061, 2022 12.

Article em En | MEDLINE | ID: mdl-36195636

Assuntos

COVID-19; Delírio; Hipocampo; Neurogênese; Idoso; Humanos; COVID-19/sangue; COVID-19/metabolismo; COVID-19/patologia; Delírio/metabolismo; Hipocampo/metabolismo; Hipocampo/patologia; Interleucina-12/metabolismo; Interleucina-12/farmacologia; Interleucina-13/metabolismo; Interleucina-13/farmacologia; Interleucina-6; Células-Tronco/metabolismo; Células-Tronco/virologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Delírio / Neurogênese / COVID-19 / Hipocampo Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Delírio / Neurogênese / COVID-19 / Hipocampo Idioma: En Ano de publicação: 2022 Tipo de documento: Article