Difluoromethylsulfonyl Imidazolium Salt for Difluoromethylation of Alkenes.
Org Lett
; 24(41): 7611-7616, 2022 10 21.
Article
em En
| MEDLINE
| ID: mdl-36201292
Herein, we describe the design and synthesis of a difluoromethylsulfonyl imidazolium salt, which can act as a radical difluoromethylation reagent to achieve the challenging amino- and oxy-difluoromethylation of alkenes. Notably, the three steps for the synthesis of the imidazolium salt do not require any tedious distillation or column chromatography purification process, and the amino- and oxy-difluoromethylation paths are simply determined by the selection of reaction solvents.
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Base de dados:
MEDLINE
Assunto principal:
Cloreto de Sódio
/
Alcenos
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article