[Mechanisms of Extracellular Vesicles Involved in Multiple Myeloma --Review].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
; 30(5): 1612-1616, 2022 Oct.
Article
em Zh
| MEDLINE
| ID: mdl-36208275
ABSTRACT
Multiple myeloma (MM) is a common hematologic tumor characterized by malignant proliferation of clonal plasma cells, the exact pathogenesis of which is not yet fully understood. The extracellular vesicles (EV) are structures released by cells into their surroundings that do not have a functional nucleus and can communicate between cells or deliver biologically active proteins and nucleic acids to target cells. EV play an important role in the interaction between myeloma cells and the bone marrow microenvironment, and they can promote MM progression. In this paper, we summarize the recent research progress in the mechanism of action of EV on MM in order to provide inspiration for exploring new strategies for MM treatment and prognostic stratification.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ácidos Nucleicos
/
Neoplasias Hematológicas
/
Vesículas Extracelulares
/
Mieloma Múltiplo
Idioma:
Zh
Ano de publicação:
2022
Tipo de documento:
Article